DRUG TITLE

Arcoxia (Etoricoxib)

THE USE OF MEDICINE

Arcoxia is used to treat acute and chronic osteoarthritis, ankylosing spondylitis, acute gouty arthritis, to relieve chronic musculoskeletal pain. This medicine contains etoricoxib, a selective inhibitor of cyclooxygenase-2 (COX-2), which blocks the formation of prostaglandins, substances responsible for the symptoms of inflammation, pain and fever. Arcoxia does not have effect on platelet function and gastrointestinal mucosa.

DOSAGE AND RECOMMENDATIONS

Take tablets by mouth with a glass of water with or without food. The recommended dosage for treatment of osteoarthritis is 60 mg once a day. For the treatment of rheumatoid arthritis and ankylosing spondylitis taking 90 mg once a day. For acute gouty arthritis take 120 mg once a day. Treatment can last for more than eight days if the daily dose is 120 mg per day. The average therapeutic dose for the treatment of pain is 60 mg taken once. Take the medicine strictly on prescription. Do not exceed recommended dose.

MISSED DOSE

Never take a double dose. When it is time for the next dose, skip the missed reception and continue to take the medicine according to schedule.

STORAGE

Store at room temperature, 59-86 F (15-30 C), away from moisture and sunlight. Protect from moisture (bathroom).

PRECAUTIONARY MEASURES

Tell your doctor if you are pregnant, planning to become pregnant or breast-feeding, were allergic to NSAIDs or Arcoxia, heart failure, myocardial infarction, bypass surgery, chest pain, stroke or mini-stroke, narrow or blocked arteries of the extremities. Do not take medication without consulting your doctor about your high blood pressure, the planned operation, diabetes, high cholesterol or smoking, which may increase the risk of coronary heart disease and atherosclerosis. Caution should be exercised in patients over 65 years. Lactose is included in the coating tablets that should be taken into account in patients with lactose deficiency.

CONTRA-INDICATIONS

Hypersensitivity to the drug, child age, pregnancy and breast-feeding, asthma, recurrent nasal polyposis, and paranasal sinuses, and intolerance of aspirin and other NSAIDs (including history), peptic ulcer disease and erosive changes of gastric mucosa and duodenal ulcers, gastric -intestinal bleeding, cerebrovascular, or any other form of bleeding, acute inflammatory bowel disease (Crohn's disease, ulcerative colitis), hemophilia and other coagulation disorders, severe heart failure, severe liver failure, or the actual liver disease, severe renal impairment, severe renal disease confirmed by hyperkalemia, since coronary artery bypass grafting (CABG), peripheral vascular disease, cerebrovascular disease, symptomatic coronary heart disease, high blood pressure is stable, accompanied by uncontrolled hypertension

SIDE EFFECT

The most common side effects are swelling of the legs, ankles, leg pain, nausea, vomiting, heartburn, indigestion, uncomfortable feeling or pain in the abdomen, diarrhea, increased blood pressure, dizziness, headache.

INTERACTION WITH  OTHER MEDICINES

Tell your doctor about all prescribed and taken non-prescription medications you are currently taking, especially warfarin, angiotensin-converting enzyme (ACE) inhibitors, acetylsalicylic acid (concurrent use may increase the risk of ulcers in the gastrointestinal tract), rifampicin (decreases Arcoxia effect).

WARNING

We provide only general information about drugs, which does not cover all directions, possible drug interactions or precautions. Information on this site may not be used for self-healing and self-diagnostics. Any special instructions for a particular patient should be coordinated with your doctor or pharmacist in charge of it. We reject the reliability of the information and errors that it may contain. We are not liable for any direct, indirect, special or other consequential damages arising from any use of the information on this site, as well as the consequences of self-medication.