DRUG TITLE

Isordil (Isosorbide Dinitrate)

DESCRIPTION

Isordil is used for treating and preventing angina caused by coronary heart disease. This medicine should be used before physical activities (exercise, sexual activity). The class of medicines: nitrates. Promotes relaxation and dilation of blood vessels.

MODE OF APPLICATION

The usual dose of isordil ranges from 5 to 20 mg, 2-3 times a day. With supportive therapy the recommended dose of 10 to 40 mg, 2-3 times a day. In some cases, allowed the appointment of higher doses, depending on the patient's condition and treatment options. To reduce the resistance of the interval between doses daily should be at least 14 hours. The optimal interval depends on the individual patient, dose and treatment regimen. You should take this medicine when you are sitting. Isordil given orally, with a little water, not mixed with food. Resolves drug under the tongue, without chewing. Isordil is taken on an empty stomach, at least 30 minutes before or 2 hours after meals.

The medicine must be taken regularly. It is forbidden to take medication more often than is necessary in large doses or over a longer time than prescribed. Contraindicated suddenly stop taking the medication. This can lead to a worsening of the patient. Before stopping this medicine you should consult a doctor.

MISSED DOSE

If you missed dose once try to take medicine, as soon as possible. If missed dose is almost identical with the time of the next dose, that medications can be missed. Contraindicated take double or extra doses.

OVERDOSE

With an overdose of the medicine should immediately call your doctor.

STORAGE

The medicine should be stored at room temperature about 25 ° C (77 ° F), protected from moisture and light, out of reach of children. The drug is released in light-resistant, waterproof containers. Do not use it after expiry date.

PRECAUTIONARY MEASURES

Even small doses may cause severe isordila hypotension, especially in the upright position. Patients with hypertension should take this medicine with caution. Hypotension is causeded by izordil may be accompanied by paradoxical bradycardia and increased angina pectoris. When a drug is necessary to consider whether the patient's earlier heart attacks or heart failure, an unusual or allergic reaction to isosorbide dinitrate, nitrates, or other medicines, foods, dyes, and preservatives, as well as pregnant or trying to get pregnant patients and nourishing.

CONTRA-INDICATIONS

Isordil  is contraindicated to the patients that have allergy to isosorbide dinitrate, or any of its components.

SIDE EFFECTS

Severe headache caused by high doses of the medicine is the best known side effect. Can dizziness, sometimes associated with changes in blood pressure. Among the side effects also include hypotension, which in severe cases is the reason for discontinuation. In rare cases, fainting may occur, increasing angina, and rebound hypertension. Isordil can cause drop in blood pressure, which leads to dizziness, heart palpitations and weakness. To avoid the risk of side effects, getting up from a sitting position, patients should slowly. As soon as possible to tell your doctor or health care professional if any of the following side effects: blue lips, fingernails, or palms, irregular or rapid heartbeat, low blood pressure, nausea, vomiting, persistent headache, unusual weakness or fatigue. Side effects such as flushing of the face, neck and rash do not require immediate medical attention, but you must tell your doctor if they persist for a long time.

INTERACTION WITH OTHER MEDICINES

Take isordil with sildenafil (Viagra), tadalafil (Cialis) and vardenafil (Levitra) can cause excessive lowering of blood pressure. Contraindicated use of the drug in combination with medications used to treat erectile dysfunction (ED), such as sildenafil, tadalafil and vardenafil, medications for high blood pressure, other drugs for the treatment of angina or heart failure.